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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8346a461b586c8c742bb13a3035cf6ec48f876476f05694de7f71a1af1979f0e' 
  AND token = 'iYeIL9gbjXztfORIJfVzNLtf3Kx1w7cxE7h9Ku+oeKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}