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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0be34331f43c8af2144ef96442e7b50f83d38b46c6a119d8913fb8201a32810a' 
  AND token = 'Mw4SRWX9jaQ7gShgTfKLgOMSrzTDqUM0rrnamp4Q3N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}