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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effb9f1d6457d75f4bca61d181aeaffa79b0231f14bf8b2638b4f7160a0b216c' 
  AND token = '5uYSGAISShGZie9y13o2Bu31nnBtBNsQ6LJZ09ZQ/ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}