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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a464aa63e54cde667d0c5327ec64a4340e93daaae1302d21a9d075e4d440b0e' 
  AND token = 'uguZwpnhStXrbAIgKAZ5QZMaf0z9iMAY9gaaV0NFT9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}