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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b383c2e20fff268d52c0a98caf06e213d35adf0fe727619c448baad62c5c1f7' 
  AND token = 'Dl5U5cb/9VVWb8pkWdkEIuayHrCNqEkUpxG+f05YPMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}