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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33d288bba7b46f9663335f4a5ac92830a348bf1f732aa9bfe0c12a3b29c87ba' 
  AND token = 'SV3x0JiHKMjeXEL1nHeUw0aQS3bNnQf484+/LnP09JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}