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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5546b6b9c92f798d7552bc849de92b9a9a7ff9ff2d2233327f652877d893834a' 
  AND token = 'n67oUmUT0O7GuE6wdm18L8C0dTUt7QffqNFzPIBOC9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}