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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb8ab376b86de42c33a11f5cb01c91276f4c6fe708284498e65e7a849bb1050' 
  AND token = 'z4M+oQpMqHtlnWygCJ3QWUMzr/tUFU8co2BUKRHiDiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}