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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ef0a48d314b32e95baf35d04e9e2093ba2021b5a65553faae6eb5f6df78ebb' 
  AND token = '5MTK8TmpFMv/FXUkJdnfmoeuMAujrxUQpwXXjGF8nJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}