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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344e16046f2ef12eef485bc58e7cb2ab371b538594d737b24d4b479724597e01' 
  AND token = '8jpG1xJCXkYVVkGg9PIkLOiUN78e+CYCVAEbnNDKBRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}