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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2159078df2020d63f09be96ab5e28154d164be4c66de38bd0a4408bcf34cb9f' 
  AND token = '5Bh2OK4obF6GU0VYAXeWruAoEydBduvslkdgUQ4HECg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}