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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a97835659f65ad6cd3c5f9db8e7c253aabb927e57223e4d1f5f7272c5d7fe33' 
  AND token = '81v82YAtBiliscn3r42PqnUmoqxb/kd8B8RCPV77PI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}