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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1621e0cf48164e95a8a58df30ae16fb52bd77bbab0f1a2e3324910970a736a6' 
  AND token = 'rAvBtxLtlRFPX89Wi6okTKY1WQkzvVORT2rOlGGuF6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}