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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d728b691d6dfad4a1cd1c4605a4b7e0c9596ee338e234f3847e4b1e9f954d00' 
  AND token = 'zpMJGAkBYavL3lLjkO6jFoHU6x25X8+ezHofea0HQpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}