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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8b060f5b2d3a56420ecacde9d42a11c7d73e43ff164819d66aa3a58537cb81' 
  AND token = 'j21fCGwrcBOnHSmq0/psGeXmInpzQr/gMdJnSbS0PLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}