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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101cde2f95165807c53598b371d73a7b210ff83ed3d1247f4b407b142889b561' 
  AND token = '8hCk1xjfxiBuDoexFS5QOXZUMpduRfibeJTJb2M9wAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}