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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478b35e42cea12db38450e69ac84ce6290f0592dbe93ea793313bc037812ab45' 
  AND token = 'E/ONeF+Rle2e6e7bhCVO4fFVBSJOfOmSwLt2sv4Vc7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}