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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2adcb27cfc1b64d37ab76a1bf7effb261477743871205c48b6a450a0ccc4d702' 
  AND token = 'FXrL0CUTpFByq5oypS6D5BULZDtO1nWaMFqvWJx31Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}