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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe4a4acf97f072d219716b94f3ec1e8e57456b637de3f79709522ccfbfa57cb' 
  AND token = 'BQezLx/KdQObvD/grMy5e76+s6NbHiM0h/sZRwf0KH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}