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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c118520f0daac1a84dd1f0ead0860185dca5cfdfe1b94c297d720819de809b5' 
  AND token = '20yEI9w98hhuCChC8v5icVWBwjJg3cDd1JwopffeDOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}