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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0265c9ecc1e0d513d86a65054529e0da410b617c536809751f83801525a1ccd' 
  AND token = 'xKC5lj6/wIxa9g3D4aejGw3LGgHWFT1PPBEwqWcqvVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}