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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5645fe6026030b282d3ac658330e651830e0e63a11fa9b239f61541873b5bd70' 
  AND token = '1hVYn80acfEDalAvb2ZCITIxE3c06widqJuoa+hEH1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}