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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7614bf2eb8bc8a10653d78a557f42de420803e83fc19e3026f6d9a548deaa350' 
  AND token = 'le7xAX5iPa9OjE71JCYKN+hVBuRKQQijp1SAkBK8nYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}