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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f1b2e537d1852228f79479af6266268efffb47707406d864f3bf36aa230c97' 
  AND token = 'il129M6pRJtxoQc1DFR8MlQHAVLXILgmdgelQft5iAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}