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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b25cd7028a8119c7b39ea8e1a14a3608477c1ce97596e9539dbf78b7ea4ce4b' 
  AND token = 'I1RPXNI9Pnu4dxcZINvVTd9Mgziiehjqk920Xi9VaxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}