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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bcf05c7a9a08f0d135b8d0f453262e389fbbd81ce629a676ca461210e1642bc' 
  AND token = 'DJlHCi2hqK5cLmYdxHU/5eh1qYKC3he/2Url7elXRaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}