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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1374e6523a76877c139205a7ee976391355c1df84bc0ca51073d2af55d68e3bb' 
  AND token = 'fWognI70NsBXonmSMOsvorjMMT6aTr2HHdSzhHul5g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}