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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e275a5ee5fde7ca554caf8e8e70d5299b862a82f00b1362348640c89047a408' 
  AND token = 'RgalE6Uo4mTy4BrUfNfs/tg2I7AQ5MUM8PWw3jQFBOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}