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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5a3732823b502aa02da014d1395bdf1526dcba8411888494acd5425f95cae7' 
  AND token = 'TT2PA3y1TtDB2QELuACYBAfT4hxh7fhPPrGmZA9HE3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}