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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e89a0d8463b10a914793bbe1a87ccb0291a7a3f311f04665e259c4d5b6a0fe21' 
  AND token = 'Njyupy3nGUtLkvCRR2h0LM6day3hzTpnNmBJir5/PlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}