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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1020905b6c250f8326e1f7238fc1b1366f5bcc73c9f77e473471ed08300630f' 
  AND token = 'gMm4K3l8j0CnmlZVctEOM3uI4i7FLlvfWTzTIWd8u/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}