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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd416c81599de15897d8e9ca9d820b62fb1e7ecf65b0a8d5f70409d1d4a0c60ac' 
  AND token = 'NmkurbFtXxCQDBzOWVmWqg7j4YVlYTDIc+Tw7Kafszg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}