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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bb421ca9878d16eb972e583a851814d716dbd1997c7416cad063e6661008db' 
  AND token = 'mDSLdZZtXHoMaxfNEY5JlOmFZ5P+AkHk6UAQj4Gpk3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}