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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e7b2cd391770a537ba2d0efd0f779a456e20cf866a8820dd74131c81306dcc' 
  AND token = '11uNxMwRP9YisVulDq9EfEhhonD8Iy+55hwhz5+qrXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}