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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b7f05b12583afc4fccf34d815ebc0c3e07cab25d8cb09ab21071648afcb0670' 
  AND token = 'WgPtTVbcCPkg+oW7oXLBZfgxnlEudSJyk/2G8wUDDwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}