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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ebf675e1d6f7f3432217751ff71367e8c27a004a50826d2affbd9320a807696' 
  AND token = '2tMGdTyV5gjo+kR3dfb4rRX9+bKYw4lFSp2OKDxy0VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}