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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110a4e3abd4707c82ec5844879ecd11fd51e21e254bca0495be78916c7cfedc0' 
  AND token = '6ZcNMf7/gtNeRx3aZo0Y5jbkMke55BLSfrnw0f5/A5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}