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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f8e025186b7c78c5b32edf1ae0e1e0ce9e07198ec501354b32fee32a48002f' 
  AND token = 'ZfLUWxsnv/OsNKGfPY2iXYYDVyprhIr4HU2IdzVasCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}