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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fcc817ca7d22816190ba5a1b951e5016898080a980e5f2bfad33c5519a0b94e' 
  AND token = '+NAsjTX4rcPa1gnOhPNoQZMwrAchF9Fbrt1RYEI3oAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}