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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c247b7c16c4b09c75868c307a2f5636779044cee922206335d0d68d9ec6138d' 
  AND token = 'ffrcTuNI3JoXh1PqL1PuUHCc4eJ6XNsERekQB3BY7Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}