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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86381af34a6b56f602c3e0f76ecaa08bf1a2c991102d61146e428c4ffbe1caf6' 
  AND token = 'GXfVTECzEobTH+QPlnfHtZkl1+iuceBxXVLTOP+CwQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}