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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ecf774006dbd5b31c102818b2e0f08cbb58448d91adf737d1b17f565957f53' 
  AND token = 'IKbywLJb3Ppeq6js8Un5d0R6i3k7XWIyEKYjkdCjbEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}