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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa9cb2b46a8110c511fdacc47bb5c1991256f11fa9efd0fd2110d434f638b7a' 
  AND token = 'fEqqUkmFSFIXm87wz1gHnTfsuGTDyT0E+t8Mj8qrfig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}