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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a9497dbab52fe4ee959c5f4a96418f92712569688096d648a838dd929ac73c' 
  AND token = 'dw7pHOunwRdgh54n0GRFWLJRWvTX/FAFqg8XNxIs4dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}