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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26b9faaad00195d9956fe13a4ee380ad9bd31b46a1da0a1ae0c340dbacc0d70f' 
  AND token = 'a5TAyrDDxbvE/I/WG0cGNAy2D4Bfjmsp3ATAO4n9FDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}