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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f28c4bc1e0fceb3a493d5203a23998c9893063c35107bdd963b81a38f71e85' 
  AND token = 'kcxDvXno6vRTrfq/v4GwvOnUuG7y8pPnv44T8XZM7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}