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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7b4fdbc9ee2faf9507e27e0f82a453a426342710f5c873bde10dba2a9eb79d2' 
  AND token = '43A8ZwVi//tCYBoXCBpBB0KNMkY3m9O+EMVg77z4vxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}