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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '054814f4f2ef38607530b2d3b1b5cd9ea70e23a57172e26574da6c24682c456f' 
  AND token = 'eJCYwdpQGiN1bm+qVA2xZW3NR+iyPJfSNHNDhBb5V5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}