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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2f64c3bedd41553136d91d80c66a76a580b7660fc37d15b7df90b76f1739d2' 
  AND token = 'OE59qRIxosNZ8HvXMNdMu1/M9c/KUPcntvz/l5ynV88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}