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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812b6f66412f343962fbbc06e7cc9207e0db42b607e8647f7a05a2075a85de33' 
  AND token = 'Mt6huZsAb2CszOzjEIPaZoGuwvsLrz3rIWAa6fXjElc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}